Early 2-mercaptoethanol-resistant antibody production in endotoxin-treated rats.
نویسندگان
چکیده
Experiments are reported concerning both natural and specific antibody production in endotoxin-treated rats.
منابع مشابه
Mercaptoethanol-resistant human serum antibodies reacting with endotoxin from Neisseria gonorrhoeae.
Sera from fifty patients with gonorrhoea, thirty with non-specific urethritis, and eighty blood donors were treated with mercaptoethanol (ME) and examined by the indirect haemagglutination test for antibodies against endotoxin from gonococci. Erythrocytes sensitized with determinant a of endotoxin from Strains 8551, V, and VII, or determinant b from Strain V were used. The percentage of sera ac...
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Sera from patients with gonorrhoea were used to study the specificity of human antibodies against determinant a of endotoxin from gonococcal strains 8551, V, and VII. The sera were tested by an indirect haemagglutination technique before and after absorption with endotoxin from the same strains. The sera were used untreated and treated with mercaptoethanol (ME). The untreated and ME-treated ser...
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Septicaemia caused by gram-negative pathogens is a dangerous infection which is associated with high incidence of liver dysfunction. The severe and acute hepatotoxicity is presumably due to massive release of endotoxin into systemic circulation after bacterial killing. The direct toxic effect of endotoxin is probably due to the increased production of reactive oxygen intermediates as O 2 - , p...
متن کاملPropofol attenuates endotoxin-induced endothelial cell injury, angiotensin-converting enzyme shedding, and lung edema.
BACKGROUND Acute lung injury (ALI) is a frequent complication in septic patients. Previously, we found that propofol, a highly lipid-soluble anesthetic, attenuates ischemia-reperfusion and oxidative lung injury in the isolated perfused rat lung. In the present study, we evaluated the effect of propofol on endotoxin-induced ALI and endothelial dysfunction. METHODS The effect of propofol on end...
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عنوان ژورنال:
- Infection and immunity
دوره 1 1 شماره
صفحات -
تاریخ انتشار 1970